About 5 results found for searched term "PG 01" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5241 | GLPG0187 | Integrin |
| GLPG0187 inhibited the progression of bone metastasis. Maximum efficacy of inhibition of bone metastasis was achieved when GLPG0187 was combined with the standard-of-care metastatic breast cancer treatments. | ||
| M7128 | PG 01 | CFTR |
| PG 01 is a potent CFTR Cl- channel potentiator.PG01 was effective against E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 was also effective against ΔF508 (Ka 0.3 μM).PG01 increased ΔF508-CFTR Cl- currents with the addition of Forskolin. F508-CFTR Cl- current after the addition of Forskolin. | ||
| M7129 | PG 01037 dihydrochloride | Others |
| PG 01037 dihydrochloride is a d 3 receptor selective antagonist. | ||
| M10169 | Vadadustat | HIF |
| AKB-6548; B-506; PG-1016548 | ||
| Vadadustat is a novel, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. | ||
| M24687 | Asunercept | TNF Receptor |
| APG101; CAN008 | ||
| Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD). | ||
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